Israeli officials staring down all-out regional war tell Axios Israel will launch a "significant retaliation" to Tuesday's massive missile attack within days that could target oil production facilities inside Iran and other strategic sites.

Iran said it fired dozens of missiles into Israel on Tuesday, a sharp escalation of the monthslong conflict between Israel and the Iran-backed militias Hezbollah and Hamas.

U.S. Vice President Kamala Harris, the Democratic presidential candidate, said on Tuesday that Iran was a "dangerous" and "destabilizing" force in the Middle East and Washington was committed to Israel's security.